Compositions and methods for modulating farnesoid X receptors

The present invention relates to compounds of Formula I,a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X rec...

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Bibliographische Detailangaben
Hauptverfasser: Roland, Jason Thomas, Tully, David Charles, Chianelli, Donatella, Molteni, Valentina, Rucker, Paul Vincent, Nelson, John, Liu, Xiaodong
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to compounds of Formula I,a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).