Processes for the preparation of sofosbuvir and intermediates thereof

The present disclosure provides procedures and intermediates for the preparation of Sofosbuvir, comprising the step of reacting a compound of formula 2: wherein R1 and R2 can independently be hydrogen or halogen, provided that at least one of R1 and R2 is a halogen.

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Bibliographische Detailangaben
Hauptverfasser:	Ariyamuthu, Sundaraselvan, Kansal, Vinod Kumar, Mistry, Dhirenkumar Natvarial, Goswami, Miteshgir Kanchangir, Achanta, Srinivas, Yazali, Venkata Subbarao
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM AGRICULTURE ANIMAL HUSBANDRY APPARATUS THEREFOR BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY DERIVATIVES THEREOF FISHING FORESTRY GENERAL METHODS OF ORGANIC CHEMISTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS TRAPPING
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Beschreibung
Zusammenfassung:	The present disclosure provides procedures and intermediates for the preparation of Sofosbuvir, comprising the step of reacting a compound of formula 2: wherein R1 and R2 can independently be hydrogen or halogen, provided that at least one of R1 and R2 is a halogen.