Method for removing viruses in a physiologically-active protein-containing sample

Method for removing viruses in a physiologically-active protein-containing sample

A method for manufacturing an antibody formulation in which DNA contaminants are removed by binding the antibody to a protein-A or probtin-G affinity column and eluting the antibody with an acidic eluting solution, preferably of low conductivity.

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Bibliographische Detailangaben
Hauptverfasser: Imamura, Akinori, Matsuhashi, Manabu, Ishii, Kimie, Takeda, Kozo, Ochi, Norimichi
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:A method for manufacturing an antibody formulation in which DNA contaminants are removed by binding the antibody to a protein-A or probtin-G affinity column and eluting the antibody with an acidic eluting solution, preferably of low conductivity.