Collection and methods for its use

The present disclosure enables methods of identifying the VH and VL class pairs in the human immune repertoire, determining the VH and VL class pairs that are most prevalent and those having favorable biophysical properties. More specifically, the collections of the present disclosure comprise the m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Enzelberger, Markus, Herrmann, Tanja, Prassler, Josef, Urlinger, Stefanie, Tiller, Thomas
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure enables methods of identifying the VH and VL class pairs in the human immune repertoire, determining the VH and VL class pairs that are most prevalent and those having favorable biophysical properties. More specifically, the collections of the present disclosure comprise the most prevalent and/or preferred VH and VL class pairings with highly diversified CDRs.