Azacyanine dyes and use thereof

The application provides fluorescent dyes, which are cyanine dyes that incorporate additional aza moieties in the indolenium heterocycles and/or in the methine chains connecting them. Symmetrical and unsymmetrical chemically reactive azacyanine dyes are described for conjugation, as well as their bi...

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Bibliographische Detailangaben
Hauptverfasser: Sinisi, Riccardo, Morales Morales, Alma Rosa, Goun, Elena A, Singh, Rajendra
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The application provides fluorescent dyes, which are cyanine dyes that incorporate additional aza moieties in the indolenium heterocycles and/or in the methine chains connecting them. Symmetrical and unsymmetrical chemically reactive azacyanine dyes are described for conjugation, as well as their bioconjugates for in-vitro and in-vivo assays and fluorescence imaging.