Managing by a hypervisor flexible adapter configurations and resources in a computer system

Managing flexible adapter configurations in a computer system including assigning an initial amount of resources to a set of empty expansion bus slots of the computer system; detecting an adapter has been attached to one of the set of empty expansion bus slots; receiving, by a hypervisor, a request for additional resources for use by the detected adapter, wherein the additional resources are in addition to the initial amount of resources assigned to the expansion bus slot occupied by the detected adapter; determining, by the hypervisor, an availability of the additional resources for the detected adapter; in response to determining that the additional resources are available for the detected adapter, assigning, by the hypervisor at runtime, the requested additional resources to the detected adapter.