Doxepin trans isomers and isomeric mixtures and methods of using the same to treat sleep disorders

The invention relates to use of the trans-(E) isomer or isomeric mixtures containing specified ratios of the trans-(E) and cis-(Z) isomers of doxepin, metabolites of doxepin, pharmaceutically-acceptable salts of doxepin and prodrugs of the same; compositions containing the same, for the treatment of...

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Bibliographische Detailangaben
Hauptverfasser: Dubé, Susan E, Kavey, Neil B
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to use of the trans-(E) isomer or isomeric mixtures containing specified ratios of the trans-(E) and cis-(Z) isomers of doxepin, metabolites of doxepin, pharmaceutically-acceptable salts of doxepin and prodrugs of the same; compositions containing the same, for the treatment of sleep disorders.