DNA polymerases with improved activity

Provided are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of primer extension methods. Also provided are related compositions, including recombinant nucleic acids, vectors, and host cells...

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Bibliographische Detailangaben
Hauptverfasser: Suko, Shawn, Bauer, Keith, Myers, Thomas W
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Provided are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of primer extension methods. Also provided are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.