Prediction of the risk of developing a disseminated infection for patients admitted to an intensive care unit

A method for predicting the risk of developing a disseminated infection in a patient admitted to intensive care having no clinical symptoms of such infection includes: determining a first dose of gelsolin G1 in a biological sample from the patient originating from a first sample taken at time T1, ca...

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Hauptverfasser: Dupin, Marilyne, Fortin, Tanguy, Roquilly, Antoine, Pons, Sylvie, Larue-Triolet, Audrey, Pachot, Alexandre, Monneret, Guillaume, Gouel-Cheron, Aurélie, Venet, Fabienne, Allaouchiche, Bernard, Asehnoune, Karim
Format: Patent
Sprache:eng
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Zusammenfassung:A method for predicting the risk of developing a disseminated infection in a patient admitted to intensive care having no clinical symptoms of such infection includes: determining a first dose of gelsolin G1 in a biological sample from the patient originating from a first sample taken at time T1, carried out between the day of intensive care admission and 48 hours afterward; determining a second dose of gelsolin G2 in a biological sample from the patient originating from a second sample taken at time T2, carried out two to three days after the first sampling; calculating the variation between the dose of gelsolin G2 and the dose of gelsolin G1, giving a Δ value; and comparing the Δ value to a threshold value S determined beforehand from two patient populations admitted to intensive care, one not having developed a disseminated infection and the other having developed such an infection.