File transfer system with dynamic file exchange control functions

Systems for dynamically controlling file transfers are provided. In some examples, a system, may receive a request to transfer a file from a first location to a second location. Prior to transferring the file, the file may be evaluated to determine whether one or more dynamic controls should be implemented. If dynamic controls should be implemented, the file may be transferred from the first location to a file distribution control computing system until an instruction to transfer the file is executed. The system may identify one or more dynamic controls to implement based on one or more machine learning datasets. In response to implementing the dynamic controls, additional data may be received. If the additional data fulfills the one or more dynamic controls, the file may be released and an instruction to transfer the file to the second location may be generated, transmitted and/or executed. In some examples, transfer may be to multiple downstream locations.