Oxa spiro derivative, preparation method therefor, and applications thereof in medicines

The present invention relates to an oxa spiro derivative, a preparation method therefor, and applications thereof in medicines. Particularly, the present invention relates to an oxa spiro derivative represented by formula (I), a preparation method therefor, and a pharmaceutical composition comprisin...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Yang, Feng, Binqiang, He, Feng, Sun, Piaoyang, Li, Xin, He, Mingxun, Tao, Weikang, Liu, Tao
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to an oxa spiro derivative, a preparation method therefor, and applications thereof in medicines. Particularly, the present invention relates to an oxa spiro derivative represented by formula (I), a preparation method therefor, and a pharmaceutical composition comprising the derivative, applications thereof as an MOR receptor agonist, and applications in the preparation of drugs for treating and/or preventing pains and pains-related diseases. Substituent groups in the formula (I) are same as definitions in the specification.