Protein melt analysis using dipyrrometheneboron difluoride compounds

According to the present teachings, systems, compositions, kits and methods for protein melt analysis are provided that utilizing a dye that is a dipyrrometheneboron difluoride compound. In some embodiments, a method comprises preparing a sample by mixing at least one protein with a dye, and applyin...

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Bibliographische Detailangaben
Hauptverfasser: Egry, Levente, Gee, Kyle
Format: Patent
Sprache:eng
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Zusammenfassung:According to the present teachings, systems, compositions, kits and methods for protein melt analysis are provided that utilizing a dye that is a dipyrrometheneboron difluoride compound. In some embodiments, a method comprises preparing a sample by mixing at least one protein with a dye, and applying a controlled heating, while recording the fluorescence emission of the sample.