Influenza virus hemagglutinin protein as a vaccine antigen

The invention relates to an influenza viruses hemagglutinin protein as a vaccine antigen against influenza viruses, in particular to a protein being a fragment of H5 hemagglutinin from highly pathogenic avian influenza virus (HPAIV) H5N1 strain, expressed in a bacterial expression system. The protei...

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Bibliographische Detailangaben
Hauptverfasser:	Lukasiewicz, Natalia, Bierczy{dot over (n)}ska-Krzysik, Anna, Borowicz, Piotr, Kapusta, Józef, Romanik, Agnieszka, Śmietanka, Krzysztof, Mikiewicz, Diana, Olszewska, Monika, Baran, Piotr, Szewczyk, Boguslaw, Sączyńska, Violetta, Minta, Zenon, Florys, Katarzyna, Plucienniczak, Andrzej, Odrowąż-Sypniewski, Michal, Cecuda-Adamczewska, Violetta, Plucienniczak, Grażyna, Sobolewska, Agnieszka, Kęsik-Brodacka, Malgorzata, Sokolowska, Iwona
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention relates to an influenza viruses hemagglutinin protein as a vaccine antigen against influenza viruses, in particular to a protein being a fragment of H5 hemagglutinin from highly pathogenic avian influenza virus (HPAIV) H5N1 strain, expressed in a bacterial expression system. The protein according to the invention is a potential ingredient of an anti-HPAIV H5N1 vaccine, administered to chickens parenterally or through mucous membranes in the presence of adjuvants. The object of the invention is also a method of obtaining the vaccine protein.