Methods of calibrating a power amplifier system to compensate for envelope amplitude misalignment

Methods of calibrating a power amplifier system to compensate for envelope amplitude misalignment are provided. In certain configurations, a method of calibrating a power amplifier system includes amplifying a radio frequency signal from a transceiver using a power amplifier and generating a supply voltage of the power amplifier using an envelope tracker, including generating a scaled envelope signal based on a power control level signal and an envelope signal, and shaping the scaled envelope signal using a shaping table generated at a target gain compression. The method further includes changing a scaling of the scaled envelope signal using a calibration module, monitoring an output of the power amplifier to determine an amount of scaling of the scaled envelope signal at which a detected gain compression of the power amplifier corresponds to the target gain compression of the shaping table, and calibrating the power amplifier system based on the determination.