Dermal filler based on crosslinked hyaluronic acid and carboxymethyl cellulose lubricant

The present invention relates to injectable dermal filler compositions in the form of a gel, comprising hyaluronic acid (HA), carboxymethyl cellulose (CMC) and, optionally, microparticles such as calcium hydroxyapatite (CaHAP) microparticles. The injectable dermal filler compositions have improved r...

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Bibliographische Detailangaben
Hauptverfasser: Hagedorn, Nadine, Villain, Franck, Belkovi, Lubin, El-Banna, Radia, Stragies, Roland
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to injectable dermal filler compositions in the form of a gel, comprising hyaluronic acid (HA), carboxymethyl cellulose (CMC) and, optionally, microparticles such as calcium hydroxyapatite (CaHAP) microparticles. The injectable dermal filler compositions have improved rheological properties while at the same time have low extrusion forces. The present invention further relates to a method for preparing such injectable dermal filler compositions and their use for cosmetic and therapeutic purposes.