Exosome-based therapeutics against neurodegenerative disorders

Methods and compositions involving exosomes or lipid nanovesicles are provided. For example, certain aspects relate to compositions comprising exosomes obtained from cells that have been induced to undergo oxidative stress or stimulated. Furthermore, some aspects of the invention provide methods of...

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Bibliographische Detailangaben
Hauptverfasser: Pusic, Kae M, Grinberg, Yelena Y, Kraig, Richard P, Pusic, Aya D
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Methods and compositions involving exosomes or lipid nanovesicles are provided. For example, certain aspects relate to compositions comprising exosomes obtained from cells that have been induced to undergo oxidative stress or stimulated. Furthermore, some aspects of the invention provide methods of treating a subject at risk or having a demyelinating disorder using the compositions.