Condensed tricyclic compounds as protein kinase inhibitors

wherein R1, R2, R3 R4, R5, R6, R7a and R7b have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. CDK8 and/or Haspin kinase) is d...

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Hauptverfasser: Hernández Higueras, Ana Isabel, Martínez González, Sonia, Gómez De La Oliva, Cristina Ana, Blanco-Aparicio, Carmen, Rivero Buceta, Virginia, Pastor Fernández, Joaquín, Riesco Fagundo, Rosario Concepción
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Sprache:eng
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Zusammenfassung:wherein R1, R2, R3 R4, R5, R6, R7a and R7b have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. CDK8 and/or Haspin kinase) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.