Process for the preparation of Apixaban and intermediates thereof

The present invention refers to novel process for the preparation of Apixaban. Further, the invention also related to a process for the preparation of intermediate of Apixaban from very basic and cheap row material i.e. Aniline which is widely commercially available. The present invention provides p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Surve, Yashwant, Ahire, Ramdas N, Sathe, Dhananjay G, Das, Arijit
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention refers to novel process for the preparation of Apixaban. Further, the invention also related to a process for the preparation of intermediate of Apixaban from very basic and cheap row material i.e. Aniline which is widely commercially available. The present invention provides process for preparation of Apixaban using a different sequence of synthetic steps and does not involve use of Ullmann reaction.