Fused pyrazole derivative having autotaxin inhibitory activity

Fused pyrazole derivative having autotaxin inhibitory activity

The present invention provides a compound of formula (I), wherein R 1 , R 2 , R 3 , R 4a , R 4b , R 5a and R 5b are as defined in the description, which has an autotaxin inhibitory activity, a pharmaceutical composition comprising the compound as an active ingredient, and a method of prevention or t...

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Bibliographische Detailangaben
Hauptverfasser: Tateno, Yusuke, Ishitani, Ryuichiro, Katou, Manabu, Yamane, Junji, Nishimasu, Hiroshi, Nureki, Osamu, Tanaka, Nobuyuki, Nagano, Tetsuo, Aoki, Junken, Kawaguchi, Mitsuyasu, Odan, Masahide, Okabe, Takayoshi, Fujikoshi, Chiaki, Kojima, Hirotatsu
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention provides a compound of formula (I), wherein R 1 , R 2 , R 3 , R 4a , R 4b , R 5a and R 5b are as defined in the description, which has an autotaxin inhibitory activity, a pharmaceutical composition comprising the compound as an active ingredient, and a method of prevention or treatment of a disease involving autotaxin, which is characterized by administering the compound.