2-(3-pyridinyl)-1H-benzimidazole derivative compound and medicine containing same

Provided is a compound represented by general formula (1) or a salt thereof as well as a medicine containing the compound or the salt. (In the formula, R 1 represents a hydrogen atom or CO 2 R a ; R 2 represents a hydrogen atom, a halogen atom, or CO 2 R a ; R 3 represents a hydrogen atom or a C1-10...

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Hauptverfasser: Ikenaga, Miho, Okumura, Yuki, Fukui, Yurie, Kobashi, Nobuya, Naruse, Mitsuhide, Izawa, Akihiro, Abe, Tsutomu, Kimura, Hiroyuki, Akama, Kei, Doi, Yoshihiro, Saji, Hideo
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Sprache:eng
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Zusammenfassung:Provided is a compound represented by general formula (1) or a salt thereof as well as a medicine containing the compound or the salt. (In the formula, R 1 represents a hydrogen atom or CO 2 R a ; R 2 represents a hydrogen atom, a halogen atom, or CO 2 R a ; R 3 represents a hydrogen atom or a C1-10 hydroxyalkyl group; R 4 represents a hydrogen atom, a hydroxy group, or a C1-10 alkoxy group; R 5 represents a C1-5 chain alkyl group in which the hydrogen atoms are optionally substituted with halogen atoms, a C3-5 cyclic alkyl group in which the hydrogen atoms are optionally substituted with halogen atoms, a C1-5 hydroxyalkyl group, or an o-, p-, or m-halobenzyl group; A represents CH or a nitrogen atom; X 1 and X 3 independently represent hydrogen atoms or halogen atoms; X 2 represents a hydrogen atom, a halogen atom, or a nitrile group; at least one of X 1 , X 2 , and X 3 represents a halogen atom; and R a independently represents a C1-10 alkyl group.)