Global routing framework of integrated circuit based on localized routing optimization

The present disclosure relates to methods, processing systems and computer program products of global routing of integrated circuits based on localized routing optimization. In certain embodiments, the method may include one or more of: defining one or more regions, one or more netgroups, and combinations thereof of an integrated circuit, associating at least one optimization objective with each region and/or each netgroup defined, generating one or more constraints for each region and/or each netgroup based on the associated optimization objectives, and performing global routing of the integrated circuit according to the one or more constraints.