Differentiation and expansion of endothelial cells from pluripotent stem cells and the in vitro formation of vasculature like structures

The disclosure is concerned among others with means and methods for obtaining endothelial cells and to means and methods for in vitro cell culture comprising endothelial cells and pericytes and/or smooth muscle cells derived from the pericytes. The endothelial cells or the pericytes and/or smooth mu...

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Bibliographische Detailangaben
Hauptverfasser: Mummery, Christine Lindsay, Orlova, Valeriya Viktorovna
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The disclosure is concerned among others with means and methods for obtaining endothelial cells and to means and methods for in vitro cell culture comprising endothelial cells and pericytes and/or smooth muscle cells derived from the pericytes. The endothelial cells or the pericytes and/or smooth muscle cells, or both, are preferably derived from in vitro differentiated pluripotent stem cells.