Attenuated Mannheimia haemolytica vaccines and methods of making and use

The present invention provides attenuated M. haemolitica strains that elicit an immune response in animal against M. haemolitica, compositions comprising said strains, methods of vaccination against M. haemolitica, and kits for use with such methods and compositions. The invention further provides m...

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Bibliographische Detailangaben
Hauptverfasser: Lawrence, Paulraj Kirubakaran, Bey, Russell F, Simonson, Randy R
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides attenuated M. haemolitica strains that elicit an immune response in animal against M. haemolitica, compositions comprising said strains, methods of vaccination against M. haemolitica, and kits for use with such methods and compositions. The invention further provides multi-valent vaccines, which provide protective immunity when administered in an effective amount to animals susceptible to "shipping fever" or bovine respiratory disease.