Factor VIII variants having a decreased cellular uptake

The present invention relates to modified coagulation factors. In particular, the present invention relates to modied Factor VIII molecules having decreased cellular uptake.

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Bibliographische Detailangaben
Hauptverfasser:	Voorberg, Johannes Jacobus, Meijer, Alexander Benjamin, Noerby, Peder Lisby, Van Den Biggelaar, Maartje, Mertens, Koenraad, Lamberth, Kasper, Olsen, Ole Hvilsted, Johnsen, Laust Bruun, Stennicke, Henning Ralf, Meems, Henriet, Kjalke, Marianne Hjortnes
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to modified coagulation factors. In particular, the present invention relates to modied Factor VIII molecules having decreased cellular uptake.