Substituted pyrazolo[1,5-A] pyridine as tropomyosin receptor kinase (TrK) inhibitors

Substituted pyrazolo[1,5-A] pyridine as tropomyosin receptor kinase (TrK) inhibitors

The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.

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Bibliographische Detailangaben
Hauptverfasser: Sasmal, Pradip Kumar, Tehim, Ashok, Mavinahalli, Nanjegowda Jagadeesh, Ahmed, Shahadat, Dattatreya, Prasanna M, Paradkar, Vidyadhar
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.