Nucleic acids and host cells expressing antibodies capable of binding to the coagulation factor XIa and uses thereof

Nucleic acids and host cells expressing antibodies capable of binding to the coagulation factor XIa and uses thereof

The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.

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Bibliographische Detailangaben
Hauptverfasser: Straßburger, Julia, Strerath, Michael, Buchmüller, Anja, Gerdes, Christoph, Dittmer, Frank, Jörißen, Hannah, Grudzinska-Goebel, Joanna, Wilmen, Andreas, Tucker, Erik, Itakura, Asako, Leung, Philberta Y, Finnern, Ricarda, Schäfer, Martina
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.