Pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mTOR inhibitors

Pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mTOR inhibitors

or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.

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Bibliographische Detailangaben
Hauptverfasser: Leroux, Frederic Georges Marie, Menear, Keith, Martin, Niall Morrison Barr, Duggan, Heather Mary Ellen, Malagu, Karine Fabienne, Smith, Graeme Cameron Murray
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.