Methods useful in the synthesis of halichondrin B analogs

Methods useful in the synthesis of halichondrin B analogs

In general, the present invention features improved methods useful for the synthesis of analogs of halichondrin B, such as eribulin and pharmaceutically acceptable salts thereof (e.g., eribulin mesylate).

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Komatsu, Yuki, Chiba, Hiroyuki, Hu, Yongbo, Zhang, Huiming, Lewis, Bryan M
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In general, the present invention features improved methods useful for the synthesis of analogs of halichondrin B, such as eribulin and pharmaceutically acceptable salts thereof (e.g., eribulin mesylate).