Display non-uniformity calibration for a virtual reality headset

An electronic display is driven to compensate for non-uniformity in a display property across display regions of the electronic display. Non-uniformity measures are determined for a set of electronic displays. A transformation is determined for converting the non-uniformity measures to transformed non-uniformity representations having fewer dimensions than a total number of the display regions in an electronic display. Using the transformation, a transformed non-uniformity representation for the electronic display is generated and stored, and an inverse transform is determined and stored. A system containing the electronic display generates correction values for the display regions by applying the inverse transformation to the transformed non-uniformity representation. Input display data for the electronic display is modified according to the generated correction values for the display regions. The electronic display is driven according the modified display data.