Macrocylic pyrimidine derivatives
wherein the variables have the meaning defined in the claims. The compounds according to the present invention have EF2K inhibitory activity and optionally also Vps34 inhibitory activity. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions compr...
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| creator | Schoentjes, Bruno Meerpoel, Lieven Berthelot, Didier Jean-Claude Embrechts, Werner Constant Johan Viellevoye, Marcel Willems, Marc Diels, Gaston Stanislas Marcella Wroblowski, Berthold Versele, Matthias Luc Aime |
| description | wherein the variables have the meaning defined in the claims. The compounds according to the present invention have EF2K inhibitory activity and optionally also Vps34 inhibitory activity. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament. |
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The compounds according to the present invention have EF2K inhibitory activity and optionally also Vps34 inhibitory activity. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180710&DB=EPODOC&CC=US&NR=10017509B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180710&DB=EPODOC&CC=US&NR=10017509B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Schoentjes, Bruno</creatorcontrib><creatorcontrib>Meerpoel, Lieven</creatorcontrib><creatorcontrib>Berthelot, Didier Jean-Claude</creatorcontrib><creatorcontrib>Embrechts, Werner Constant Johan</creatorcontrib><creatorcontrib>Viellevoye, Marcel</creatorcontrib><creatorcontrib>Willems, Marc</creatorcontrib><creatorcontrib>Diels, Gaston Stanislas Marcella</creatorcontrib><creatorcontrib>Wroblowski, Berthold</creatorcontrib><creatorcontrib>Versele, Matthias Luc Aime</creatorcontrib><title>Macrocylic pyrimidine derivatives</title><description>wherein the variables have the meaning defined in the claims. 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The compounds according to the present invention have EF2K inhibitory activity and optionally also Vps34 inhibitory activity. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.</abstract><oa>free_for_read</oa></addata></record> |
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| title | Macrocylic pyrimidine derivatives |
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