INHIBITORS OF THE HEDGEHOG PATHWAY

The present invention is directed to a compound of Formula (I) or a single isomer thereof; where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula I, and methods of using a Compound of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	RIDGWAY, BRIAN HUGH, BAJJALIEH, WILLIAM, WANG, YONG, TESFAI, ZEROM, HUYNH, TAI PHAT, FORSYTH, TIMOTHY PATRICK, CHEN, JEFF, MANN, GRACE, SHI, XIAN, MAC, MORRISON B, TAKEUCHI, CRAIG STACY, SANGALANG, JOAN C, MARLOWE, CHARLES K, EPSHTEYN, SERGEY, KIM, BYUNG GYU, BAHCECI, SULEYMAN, LEAHY, JAMES W, LEE, MATTHEW SANGYUP, LEWIS, GARY L
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention is directed to a compound of Formula (I) or a single isomer thereof; where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula I, and methods of using a Compound of Formula (I) to treat cancer., (I) Данное изобретение касается соединения формулы (I)Iили ее фармацевтически приемлемой соли, гидрата, сольвата или их комбинации; а также применения соединения формулы (I) для лечения рака. Даний винахід стосується сполуки формули (І)Iабо її фармацевтично прийнятної солі, гідрату, сольвату або їх комбінації; а також застосування сполуки формули (І) для лікування раку.