METHOD FOR PRODUCING COATED TABLETS OF ANTIBACTERIAL DRUG

The method for producing the coated tablets of the antibacterial drug comprises mixing of the active substance with the excipients, the moistening of the mixture, the wet granulation of the mixture, the drying of the wet granulate, the powdering of the granulate, the dry granulation, the tableting,...

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Hauptverfasser: DEMCHENKO INNA BORYSIVNA, MOMOT VITALII MYKOLAIOVYCH, KOVALIOVA ALLA MYKHAILIVNA, TYMCHENKO MYKOLA MYKHAILOVYCH, SHKLIAIEV SERHII ANATOLIIOVYCH, HOLOVKO NATALIA VOLODYMYRIVNA, HEORHIEVSKYI HENNADII VIKTOROVYCH, KOMISARENKO SERHII MYKOLAIOVYCH, KOVALCHUK NATALIA IVANIVNA, KOMISARENKO ANDRII MYKOLAIOVYCH
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Sprache:eng
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Zusammenfassung:The method for producing the coated tablets of the antibacterial drug comprises mixing of the active substance with the excipients, the moistening of the mixture, the wet granulation of the mixture, the drying of the wet granulate, the powdering of the granulate, the dry granulation, the tableting, and coating the cores of the tablets with the mixture containing titanium dioxide and metylcellulose. Pefloxacin mesilate dehydrate is used as an active substance, the potato starch is used as the excipient. The aqueous solution of gelatin is used for moistening of the mixture.