METHOD FOR SIMULATING DIABETIC FOOT

METHOD FOR SIMULATING DIABETIC FOOT

The proposed method for simulating diabetic foot consists in subcutaneously introducing, to the experimental animal, 5 % alloxan solution to the amount of 150 mg per 1 kg of the weight of the animal body within 10 hours after meal, than introducing, after 13 days, in the interscapular zone of the an...

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Hauptverfasser: POLIANSKYI OLEH IHOROVYCH, KNUT RUSLAN PETROVYCH, LIKSUTOV YEVHEN ANDRIIOVYCH, BUREHA OLEKSANDR STEPANOVYCH, SYDORCHUK RUSLAN IHOROVYCH, MYKHAILOVSKYI OLEKSANDR VOLODYMYROVYCH, BILYK IVAN SEMENOVYCH
Format: Patent
Sprache:eng
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Zusammenfassung:The proposed method for simulating diabetic foot consists in subcutaneously introducing, to the experimental animal, 5 % alloxan solution to the amount of 150 mg per 1 kg of the weight of the animal body within 10 hours after meal, than introducing, after 13 days, in the interscapular zone of the animal, mixture of aerobic and anaerobic microorganisms (S.aureus, S.epidermidis, B.fragilis, Peptococcus spp. and Fusobacterium spp.) to the amount of 107 ... 109 microorganisms per 1 ml of the solution be using a scarificator 1.5 x 2.5 cm in dimensions.