METHOD FOR DETERMINING THE DEGREE OF THE CYTOTOXICITY OF BIOLOGICALLY ACTIVE CHEMICAL COMPOUND OR PHARMACOLOGICAL PREPARATION

The proposed method for determining the degree of the cytotoxicity of biologically active chemical compound or pharmacological preparation consists in providing the interaction of water solutions of the analyzed substance, with different concentrations, with the cells of infusorium Colpoda steinii,...

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Hauptverfasser:	VYNOKHODOV DMYTRO OLEHOVYCH, LOZYTSKYI VIKTOR PETROVYCH, BOSCHENKO YURII ANATOLIIOVYCH, FEDCHUK ALLA SEMENIVNA, HRYDINA TETIANA LEONIDIVNA, SLAVINA NINA HEORHIIVNA, POZDNIAKOVA LIUDMYLA IVANIVNA, HRYHORASHEVA IRYNA MYKOLAIVNA, POLEZHAIEV FIAL IBRAGIMOVYCH
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The proposed method for determining the degree of the cytotoxicity of biologically active chemical compound or pharmacological preparation consists in providing the interaction of water solutions of the analyzed substance, with different concentrations, with the cells of infusorium Colpoda steinii, determining the indicators that characterize the vitality of the infusoria within three hours after the start of the interaction, and determining the maximal allowable concentration of the substance by the values of the said indicators.