METHOD FOR PREPARING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-[1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAPHTHYRIDINE

METHOD FOR PREPARING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-[1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAPHTHYRIDINE

The present invention covers a method for preparing 2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine ("the compound of formula (I)" in the following) as well as intermediate compounds useful in the preparation of the compound of formula (I)...

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Hauptverfasser: Rubenbauer, Philipp, van der Haas, Hendricus, Nicolaas, Sebastiaan, Hoogeveen, Sonja, Elisabeth, van Oers, Matthijs, Cornelis, Maria, Platzek, Johannes, Dekker, Jeroen, Alexander, Gieling, Reinerus, Gerardus
Format: Patent
Sprache:eng ; ukr
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Zusammenfassung:The present invention covers a method for preparing 2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine ("the compound of formula (I)" in the following) as well as intermediate compounds useful in the preparation of the compound of formula (I). The present invention also covers polymorphic form B of the compound of formula (I) with very high purity. (I) Винахід стосується способу одержання 2-[(3R)-3-метилморфолін-4-іл]-4-(1-метил-1H-піразол-5-іл)-8-(1H-піразол-5-іл)-1,7-нафтиридину ("сполука формули (I)" надалі), а також проміжних сполук, придатних для одержання сполуки формули (I): (I).