BISPECIFIC ANTIBODY CONSTRUCTS BINDING DLL3 AND CD3
The present invention relates a bispecific antibody construct comprising a first binding domain which hinds to human DLL3 on the surface of a target cell and a second binding domain which binds to human СD3 on the surface of a Tcell. Moreover, the invention provides a polynucleotide encoding the ant...
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Sprache: | eng ; ukr |
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Zusammenfassung: | The present invention relates a bispecific antibody construct comprising a first binding domain which hinds to human DLL3 on the surface of a target cell and a second binding domain which binds to human СD3 on the surface of a Tcell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transacted with said polynucleotide or sector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
The present invention relates a bispecific antibody construct comprising a first binding domain which hinds to human DLL3 on the surface of a target cell and a second binding domain which binds to human СD3 on the surface of a Tcell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transacted with said polynucleotide or sector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct. |
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