ANTICANCER COMPOUNDS

Anticancer compounds of general formula (I), wherein R1 to R4 take various meanings, for use in the treatment of cancer. A novel Labrenziasp. strain named PHM005 with Accession Deposit Number CECT-9225, a method of producing compounds of the invention and analogues thereof by using the PHM005 strain...

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Hauptverfasser: Schleissner Sánchez, María del Carmen, Cañedo Hernández, Librada María, Zúñiga Girón, Paz, de la Calle Verdú, Fernando, Rodríguez Ramos, María Pilar
Format: Patent
Sprache:eng ; ukr
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Zusammenfassung:Anticancer compounds of general formula (I), wherein R1 to R4 take various meanings, for use in the treatment of cancer. A novel Labrenziasp. strain named PHM005 with Accession Deposit Number CECT-9225, a method of producing compounds of the invention and analogues thereof by using the PHM005 strain and the Lab gene cluster codifying the biosynthesis of pederin-like and onnamide-like compounds are also provided. , I Винахід стосується сполук загальної формули I I для застосування для лікування злоякісного новоутворення. Запропоновано також спосіб отримання сполук за даним винаходом.