CYCLIZED SULFAMOYLARYLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B

Inhibitors of HBV replication of Formula (І-A), including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Ra to Rd, and R1 to R8 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositio...

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Hauptverfasser: Raboisson, Pierre, Jean-Marie, Bernard, Grosse, Sandrine, Céline, Haché, Geerwin, Yvonne, Paul, Vendeville, Sandrine, Marie, Helene, Rombouts, Geert, Hu, Lili, Vandyck, Koen, Pieters, Serge, Maria, Aloysius, Last, Stefaan, Julien, Verschueren, Wim, Gaston, Demin, Samuël, Dominique
Format: Patent
Sprache:eng ; ukr
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Zusammenfassung:Inhibitors of HBV replication of Formula (І-A), including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Ra to Rd, and R1 to R8 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.