Modified guide rnas

This disclosure relates to modified single and dual guide RNAs having improved in vitro and in vivo activity in gene editing methods.

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Hauptverfasser: SMITH, AMY MADISON RHODEN, STRAPPS, WALTER, MORRISSEY, DAVID V
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Sprache:chi ; eng
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creator SMITH, AMY MADISON RHODEN
STRAPPS, WALTER
MORRISSEY, DAVID V
description This disclosure relates to modified single and dual guide RNAs having improved in vitro and in vivo activity in gene editing methods.
format Patent
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language chi ; eng
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Modified guide rnas
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