TWI833242B

The present application relates to the field of biomedical technology, and specifically, provides an anti-PD-1 humanized antibody or an antigen-binding fragment thereof and an application thereof. The antibody can efficiently and specifically bind to PD-1, and can effectively block the binding of th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZHANG, ZHE, GONG, CHUNXI, HUO, YONGTING, LI, FAN, LU, LISHENG, LU, DI, FU, JUN
Format: Patent
Sprache:chi
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Beschreibung
Zusammenfassung:The present application relates to the field of biomedical technology, and specifically, provides an anti-PD-1 humanized antibody or an antigen-binding fragment thereof and an application thereof. The antibody can efficiently and specifically bind to PD-1, and can effectively block the binding of the PD-1 to PD-L1 and PD-L2. Therefore, the antibody or the antigen-binding fragment thereof, and its related nucleic acid, vector, cell or pharmaceutical composition can be used to prepare a medicament of PD-1-mediated diseases or conditions.