Molecules with solubility tag and related methods

Molecules with solubility tag and related methods

The present disclosure relates to molecules comprising a targeting moiety, at least one payload wherein said at least one payload is a therapeutic agent or a detectable lable, a linker/linkers covalently linking said payload/payloads and said targeting moiety, and at least one solubility tag, wherei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RICHTER-SANDER, ULRIKE, KORPUS, CHRISTOPH, VON HAGEN, JOERG, KELLY, SVEN, DEUTSCH, CARL, CRASSIER, HELENE
Format: Patent
Sprache:chi ; eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure relates to molecules comprising a targeting moiety, at least one payload wherein said at least one payload is a therapeutic agent or a detectable lable, a linker/linkers covalently linking said payload/payloads and said targeting moiety, and at least one solubility tag, wherein said solubility tag comprises at least 3 and up to 12 monosaccharide units.