Fused ring compound having urea structure and use thereof

The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating/preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular dise...

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Bibliographische Detailangaben
Hauptverfasser:	TSUJI, TAKASHI, NAKAMURA, TSUYOSHI, TERAYAMA, KOJI, TANAKA, JUN, AKIU, MAYUKO, YOKOYAMA, MIKA, PINKERTON, ANTHONY B, SESSIONS, EDWARD HAMPTON
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating/preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular disease, and muscle wasting disorder.The present invention provides a compound represented by following formula (I) or a pharmacologically acceptable salt:wherein A, B, R1, R2 and R3 represent the same meanings as in the claims.