Aggrecan binding immunoglobulins

The present invention relates to immunoglobulins that specifically bind Aggrecan and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypepti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HERMANS, GUY, BESTE, GERALD, TOLEIKIS, LARS, STEFFENSEN, SOREN, GUHRING, HANS, LADEL, CHRISTOPH
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention relates to immunoglobulins that specifically bind Aggrecan and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the immunoglobulins of the present invention inhibit the activity of Aggrecan.