Treatment of hematological cancer with pd-1/cd3 bispecific protein

The problem to be solved by the present invention is to provide a new agent for preventing, suppressing the progression of symptoms of or the recurrence of, and/or treating hematological cancer.The inventors of the present invention have diligently studied, and focused on bispecific proteins having...

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Hauptverfasser: SHIMBO, TAKUYA, SHIBAYAMA, SHIRO
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creator SHIMBO, TAKUYA
SHIBAYAMA, SHIRO
description The problem to be solved by the present invention is to provide a new agent for preventing, suppressing the progression of symptoms of or the recurrence of, and/or treating hematological cancer.The inventors of the present invention have diligently studied, and focused on bispecific proteins having a first arm specifically binding to PD-1 and a second arm specifically binding to CD3 (preferably, PD-1/CD3 bispecific antibody or antibody fragment thereof) as a substance to dissolve such a problem, and found that they are useful for preventing, suppressing the progression of symptoms of or the recurrence of, and/or treating hematological cancer.
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language chi ; eng
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Treatment of hematological cancer with pd-1/cd3 bispecific protein
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