Treatment of hematological cancer with pd-1/cd3 bispecific protein

The problem to be solved by the present invention is to provide a new agent for preventing, suppressing the progression of symptoms of or the recurrence of, and/or treating hematological cancer.The inventors of the present invention have diligently studied, and focused on bispecific proteins having...

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Bibliographische Detailangaben
Hauptverfasser:	SHIMBO, TAKUYA, SHIBAYAMA, SHIRO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The problem to be solved by the present invention is to provide a new agent for preventing, suppressing the progression of symptoms of or the recurrence of, and/or treating hematological cancer.The inventors of the present invention have diligently studied, and focused on bispecific proteins having a first arm specifically binding to PD-1 and a second arm specifically binding to CD3 (preferably, PD-1/CD3 bispecific antibody or antibody fragment thereof) as a substance to dissolve such a problem, and found that they are useful for preventing, suppressing the progression of symptoms of or the recurrence of, and/or treating hematological cancer.