A new crystalline form of obeticholic acid and preparation method thereof

The present invention relates to a new crystalline form of obeticholic acid and a preparation method therefor. In particular, the present invention relates to crystal form E of obeticholic acid and a preparation method therefor. The crystalline form is very stable, and the solvent residue is low, an...

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Hauptverfasser: ZHANG, SHUNJI, TIAN, WEIWEI, ZHU, CHANGZHEN, WANG, SHENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to a new crystalline form of obeticholic acid and a preparation method therefor. In particular, the present invention relates to crystal form E of obeticholic acid and a preparation method therefor. The crystalline form is very stable, and the solvent residue is low, and the crystalline form is suitable for industrial production. Obeticholic acid has the following structure: