Complexes of abiraterone acetate, process for the preparation thereof and pharmaceutical compositions containing them

The present disclosure relates to pharmaceutically acceptable complex formulae comprising complexes of Abiraterone acetate and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulae of the present disclosure h...

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Bibliographische Detailangaben
Hauptverfasser: FILIPCSEI, GENOVEVA, SOLYMOSI, TAMAS, OTVOS, ZSOLT, ANGI, REKA, JORDAN, TAMAS, BASA-DENES, ORSOLYA, GLAVINAS, HRISTOS
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present disclosure relates to pharmaceutically acceptable complex formulae comprising complexes of Abiraterone acetate and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulae of the present disclosure have improved physicochemical properties which results in reduced food effect which allows significant dose reduction and the abandoning of the requirement of taking the drug on an empty stomach.