Accurate desensitization estimation of a receiver

Described herein are technologies related to an implementation of desensitization estimation in a receiver of a portable device in co-existence with a concurrently operating transmitter. Accurately estimating the total signal distortion or receiver desensitization, e.g. during a calibration process in a radio frequency module production or system manufacturing, allows to perform a corrective algorithm to mitigate effects of the estimated total distortion during operation of the portable device, i.e. to reduce the overall receiver desensitization to an acceptable level.