Gip receptor-active glucagon compounds

Glucagon peptides with increased GIP activity are provided, optionally with GLP-1 and/or glucagon activity. In some embodiments, C-terminally extended glucagon peptides comprising an amino acid sequence substantially similar to native glucagon are provided herein.

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Bibliographische Detailangaben
Hauptverfasser: CHABENNE, JOSEPH, DAY, JONATHAN, DIMARCHI, MARIA, TAO, MA, SMILEY, DAVID, PATTERSON, JAMES, DIMARCHI, RICHARD D, WARD, BRIAN C
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Glucagon peptides with increased GIP activity are provided, optionally with GLP-1 and/or glucagon activity. In some embodiments, C-terminally extended glucagon peptides comprising an amino acid sequence substantially similar to native glucagon are provided herein.