Preparation of pregabalin and related compounds

Materials and methods for preparing (S)-(+)-3-aminomethyl-5-methyl-hexanoic acid and structurally related compounds via enzymatic kinetic resolution are disclosed.

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Bibliographische Detailangaben
Hauptverfasser: TAO, JUNHUA, TULLY, WILLIAM EUGENE, KELLEHER, PATRICK GERARD THOMAS, HU, SHANGHUI, MARTINEZ, CARLOS ALBERTO, DUMOND, YVES RENE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Materials and methods for preparing (S)-(+)-3-aminomethyl-5-methyl-hexanoic acid and structurally related compounds via enzymatic kinetic resolution are disclosed.